Lipid Mediator Panel

Overview
Advantages
Applications
Method

Overview

Lipid Mediator Panel

Inflammatory lipid mediators are potent signal molecules derived from the oxidation of phospholipids and ω-6 polyunsaturated fatty acids.

They play significant roles in regulating a multitude of physiological and cellular processes.

Inflammatory lipid mediators are implicated in numerous diseases, including:

  • Inflammatory disorders
  • Cancer

  • Heart diseases

  • Metabolic diseases

  • Neurological diseases

Applications

  • This panel measures the eleven key species of inflammatory lipid mediators that are prominent in human plasma

Covered lipid mediators classes are:

  • prostaglandins
  • hydroxyeicosatetraenoic acids (HETE)
  • hydroxyoctadecadienoic acids (HODE)
  • dihydroxy-octadecenoic acids (diHOME)

And their fatty acid precursors:

  • linoleic acid
  • arachidonic acid

  • Advantages

  • Reproducible Results

  • Comprehensive panel covering inflammatory lipid mediator pathways

  • Fully quantitative LC-MS/MS method with minimum of 6 to 8 calibrators per analyte matching stable isotope labeled internal standards for each analyte

  • Low sample volume requirement

  • Method

  • Analysis by LC-MS/MS

  • Sciex Exion UHPLC, coupled to a Sciex 7500+ Triple Quadrupole Mass Spectrometer

Measured Lipid Mediators & Metabolites

Analytes
12, 13-DiHOME 12-HETE
9, 10-DiHOME 5-HETE
13-HODE Linoleate
9-HODE Arachidonate
15-HETE Prostaglandin E2
Prostaglandin F2α

Sample Requirements

Sample Matrix Sample Amount
Plasma/Serum 200 µL

View More Offerings

Lipid Mediators2024-02-03T22:56:05+00:00
Lipid Mediators

Lipid Mediators

Short-Chain Fatty Acids2024-02-03T22:55:48+00:00
Short-Chain Fatty Acids

Short-Chain Fatty Acids

Steroid Hormones2024-02-03T22:55:21+00:00
Steroid Hormones

Steroid Hormones

Gut Microbiome2024-02-05T20:35:25+00:00
Gut Microbiome

Gut Microbiome

Human Milk Oligosaccharides2024-02-03T22:54:02+00:00
Human Milk Oligosaccharides

Human Milk Oligosaccharides

Custom Assay Development2024-01-15T21:39:08+00:00
Custom Assay Development

Custom Assay Development

Skin Age2024-02-03T22:52:44+00:00
Skin Age

Skin Age

Central Carbon & Energy Metabolism2024-02-05T19:02:14+00:00
Central Carbon & Energy Metabolism

Central Carbon & Energy Metabolism

Contact Us Today

Partner with Precion and let our team develop your next superior assay.