Lipid Mediator Panel
Inflammatory lipid mediators are potent signal molecules derived from the oxidation of phospholipids and ω-6 polyunsaturated fatty acids. They play significant roles in regulating a multitude of physiological and cellular processes.
Inflammatory lipid mediators are implicated in numerous diseases, including inflammatory disorders, cancer, heart diseases, metabolic diseases, and neurological diseases.
This panel measures the eleven key species of inflammatory lipid mediators that are prominent in human plasma.
Covered lipid mediators classes are:
hydroxyeicosatetraenoic acids (HETE)
hydroxyoctadecadienoic acids (HODE)
dihydroxy-octadecenoic acids (diHOME)
fatty acid precursors linoleic acid and arachidonic acid
Key Advantage – Reproducible Results
Comprehensive panel covering inflammatory lipid mediator pathways
Fully quantitative LC-MS/MS method with minimum of 6 to 8 calibrators per analyte matching stable labeled internal standards for each analyte
Calibrator and quality control sample precision (% CV) typically <10%
Matching stable labelled internal standards for each analyte
Low sample volume requirement
Analytical Method & Instrumentation
Analysis by LC-MS/MS
Sciex Exion UHPLC, coupled to a Sciex 7500+ Triple Quadrupole Mass Spectrometer